Black Seed Oil For Cancer
(Includes Links To 24 Research Articles!)
The Ancients of many and varied traditional forms of medicine such as Ayurveda, Unani-Tibb and Siddha, have used this little black seed of goodness for millenia. This is an almost magical, natural gift of the Earth!
(Includes Links To 24 Research Articles!)
The Ancients of many and varied traditional forms of medicine such as Ayurveda, Unani-Tibb and Siddha, have used this little black seed of goodness for millenia. This is an almost magical, natural gift of the Earth!
Black seed oil, Nigella sativa, is ranked very highly among the world of herbal plants. When we are talking about the enormous volume of research that has been conducted on black seed, it is THE MOST heavily scrutinized plant that we have.
Scientists have been looking at Nigella sativa as a medicinal treatment for decades, but it’s only now that we the public are beginning to hear about it.
Also going by the name cumin oil, it is full of the amazing healing abilities of it’s most active ingredient which is named Thymoquinone (TQ)
Scientists have been looking at Nigella sativa as a medicinal treatment for decades, but it’s only now that we the public are beginning to hear about it.
Also going by the name cumin oil, it is full of the amazing healing abilities of it’s most active ingredient which is named Thymoquinone (TQ)
Other Active Ingredients Of Black Cumin Seed Oil Include:
- Alphahederin
- Carvacrol
- Dithymoquinone
- Nigellicine
- Nigellidine
- Nigellimine
- Thymohydroquinone
- Thymol
- Alphahederin
- Carvacrol
- Dithymoquinone
- Nigellicine
- Nigellidine
- Nigellimine
- Thymohydroquinone
- Thymol
Black Seed Oil For Cancer
There are so many research studies that show great results for black seed oil treatments related to it’s cancer killing and anti inflammatory properties.
Even though the scientists say that more studies are needed to determine exactly what is going on in the molecular and cellular mechanisms underlying the anti-cancer effects of N. sativa, it’s worth a try. Especially seeing as this is a non toxic (at dose levels) material.
What the scientists want to discover are the exact signalling pathways that helps black cumin seed oil play such a big role in killing cancer.
There are so many research studies that show great results for black seed oil treatments related to it’s cancer killing and anti inflammatory properties.
Even though the scientists say that more studies are needed to determine exactly what is going on in the molecular and cellular mechanisms underlying the anti-cancer effects of N. sativa, it’s worth a try. Especially seeing as this is a non toxic (at dose levels) material.
What the scientists want to discover are the exact signalling pathways that helps black cumin seed oil play such a big role in killing cancer.
Many Pathways To Healing
“The anticancer effect(s) of thymoquinone are mediated through different modes of action, including anti-proliferation, apoptosis induction, cell cycle arrest, ROS generation and anti-metastasis/anti-angiogenesis. In addition, this quinone was found to exhibit anticancer activity through the modulation of multiple molecular targets, including p53, p73, PTEN, STAT3, PPAR-γ, activation of caspases and generation of ROS.”
“Thymoquinone is an active ingredient isolated from Nigella sativa and has been investigated for its anti-oxidant, anti-inflammatory and anticancer activities in both in vitro and in vivo models since its first extraction in 1960s.
“The anticancer effect(s) of thymoquinone are mediated through different modes of action, including anti-proliferation, apoptosis induction, cell cycle arrest, ROS generation and anti-metastasis/anti-angiogenesis. In addition, this quinone was found to exhibit anticancer activity through the modulation of multiple molecular targets, including p53, p73, PTEN, STAT3, PPAR-γ, activation of caspases and generation of ROS.”
“Thymoquinone is an active ingredient isolated from Nigella sativa and has been investigated for its anti-oxidant, anti-inflammatory and anticancer activities in both in vitro and in vivo models since its first extraction in 1960s.
Its anti-oxidant/anti-inflammatory effect has been reported in various disease models, including encephalomyelitis, diabetes, asthma and carcinogenesis.
In addition, thymoquinone could act as a free radical and superoxide radical scavenger, as well as preserving the activity of various anti-oxidant enzymes such as catalase, glutathione peroxidase and glutathione-S-transferase.
In addition, thymoquinone could act as a free radical and superoxide radical scavenger, as well as preserving the activity of various anti-oxidant enzymes such as catalase, glutathione peroxidase and glutathione-S-transferase.
Here’s Some More Hope For Cancer Treatment
“As non invasive lesions progress to malignancy, the precursor period provides a window for cancer therapies that can interfere with neoplastic progression. Thymoquinone (Tq), a major bioactive component of essential oil from Nigella sativa's seeds, has demonstrated antineoplastic activities in multiple cancers” - https://www.ncbi.nlm.nih.gov/pubmed/28105374
“A cell study conducted at the International Immuno – Biology Research Laboratory in South Carolina showed that when incubated with Nigella extract, cancer cells were unable to produce fibroblast growth factor and the protein collagenase, both are necessary for blood-vessel growth into the tumor. Without a blood supply, a tumor cannot grow”
“As non invasive lesions progress to malignancy, the precursor period provides a window for cancer therapies that can interfere with neoplastic progression. Thymoquinone (Tq), a major bioactive component of essential oil from Nigella sativa's seeds, has demonstrated antineoplastic activities in multiple cancers” - https://www.ncbi.nlm.nih.gov/pubmed/28105374
“A cell study conducted at the International Immuno – Biology Research Laboratory in South Carolina showed that when incubated with Nigella extract, cancer cells were unable to produce fibroblast growth factor and the protein collagenase, both are necessary for blood-vessel growth into the tumor. Without a blood supply, a tumor cannot grow”
“Thymoquinone blocked angiogenesis in vitro and in vivo, prevented tumor angiogenesis in a xenograft human prostate cancer (PC3) model in mouse, and inhibited human prostate tumor growth at low dosage with almost no chemotoxic side effects.” - http://mct.aacrjournals.org/content/7/7/1789
“Substantial in vitro data suggest that thymoquinone may be beneficial in treatment of glial tumors. However, there is no clinical study investigating its antitumor effects.
In fact, thymoquinone suppresses growth and invasion, and induces apoptosis of glial tumor cells via degrading tubulins and inhibiting 20S proteasome, telomerase, autophagy, FAK and metalloproteinases. A simple and easily available agent may be a promising adjunctive treatment option in neurological and neurosurgical practice.” - http://www.sciencedirect.com/science/article/pii/S0753332216307302
“Substantial in vitro data suggest that thymoquinone may be beneficial in treatment of glial tumors. However, there is no clinical study investigating its antitumor effects.
In fact, thymoquinone suppresses growth and invasion, and induces apoptosis of glial tumor cells via degrading tubulins and inhibiting 20S proteasome, telomerase, autophagy, FAK and metalloproteinases. A simple and easily available agent may be a promising adjunctive treatment option in neurological and neurosurgical practice.” - http://www.sciencedirect.com/science/article/pii/S0753332216307302
Meh, I'm a hippy and I consider putting up cancer pics to be in bad taste. So, Peace to you! :o)
More Black Seed Oil And Cancer Research Papers:
The rest of the research papers - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052360/
https://www.ncbi.nlm.nih.gov/pubmed/27698868
“TQ was found to increase sub-G1 accumulation and annexin-V positive staining, indicating apoptotic induction.” -
https://www.ncbi.nlm.nih.gov/pubmed/21679698
“Cytotoxicity of Nigella sativa seed oil and extract against human lung cancer cell line.” - https://www.ncbi.nlm.nih.gov/pubmed/24568529
“Cellular responses with thymoquinone treatment in human breast cancer cell line MCF-7.” - https://www.ncbi.nlm.nih.gov/pubmed/23900121
The rest of the research papers - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052360/
https://www.ncbi.nlm.nih.gov/pubmed/27698868
“TQ was found to increase sub-G1 accumulation and annexin-V positive staining, indicating apoptotic induction.” -
https://www.ncbi.nlm.nih.gov/pubmed/21679698
“Cytotoxicity of Nigella sativa seed oil and extract against human lung cancer cell line.” - https://www.ncbi.nlm.nih.gov/pubmed/24568529
“Cellular responses with thymoquinone treatment in human breast cancer cell line MCF-7.” - https://www.ncbi.nlm.nih.gov/pubmed/23900121
“Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein.” - https://www.ncbi.nlm.nih.gov/pubmed/21609759
“A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells.” - https://www.ncbi.nlm.nih.gov/pubmed/17487093
“In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone.” - https://www.ncbi.nlm.nih.gov/pubmed/12469192
“A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells.” - https://www.ncbi.nlm.nih.gov/pubmed/17487093
“In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone.” - https://www.ncbi.nlm.nih.gov/pubmed/12469192
“Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.” - https://www.ncbi.nlm.nih.gov/pubmed/15375533
“Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo.” - https://www.ncbi.nlm.nih.gov/pubmed/20594324
“Effect of Thymoquinone on P53 Gene Expression and Consequence Apoptosis in Breast Cancer Cell Line.” - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837800/
“Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cells.” - https://www.ncbi.nlm.nih.gov/pubmed/24039814
“Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo.” - https://www.ncbi.nlm.nih.gov/pubmed/20594324
“Effect of Thymoquinone on P53 Gene Expression and Consequence Apoptosis in Breast Cancer Cell Line.” - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837800/
“Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cells.” - https://www.ncbi.nlm.nih.gov/pubmed/24039814
“Antitumor and anti-angiogenesis effects of thymoquinone on osteosarcoma through the NF-κB pathway.” - https://www.ncbi.nlm.nih.gov/pubmed/23232982
Even More Research!
https://www.ncbi.nlm.nih.gov/pubmed/22005518
http://idosi.org/gv/gv2(4)08/9.pdf
http://www.iasj.net/iasj?func=fulltext&aId=42676
https://www.ncbi.nlm.nih.gov/pubmed/16314136
https://www.ncbi.nlm.nih.gov/pubmed/19768141
https://www.ncbi.nlm.nih.gov/pubmed/23513732
https://www.ncbi.nlm.nih.gov/pubmed/21609759
Even More Research!
https://www.ncbi.nlm.nih.gov/pubmed/22005518
http://idosi.org/gv/gv2(4)08/9.pdf
http://www.iasj.net/iasj?func=fulltext&aId=42676
https://www.ncbi.nlm.nih.gov/pubmed/16314136
https://www.ncbi.nlm.nih.gov/pubmed/19768141
https://www.ncbi.nlm.nih.gov/pubmed/23513732
https://www.ncbi.nlm.nih.gov/pubmed/21609759
I hope you have found some information here that you can put to good use for you and yours.
As always, do your own research and become your own health advocate!
Good luck on your natural health journey!
As always, do your own research and become your own health advocate!
Good luck on your natural health journey!
***If you have a great natural health healing story, please let me know if you would like to be interviewed (a quick 5/6 questions, can be answered via email) and for your experience to be published in my upcoming book called “Natural Healing Health Pathways – Stories From Beyond A Death Sentence”
References
Included in the body of the article for ease of reference.
Included in the body of the article for ease of reference.